【摘要】目的 研究透析供水系统不同形式的消毒方式的效果。 方法 采用甲醛化学消毒和热消毒，其中热消毒频率分别为1次/d、1次/3d和1次/w,消毒后对菌落数和内毒素进行比较。 结果 热消毒组菌落为(38.90±36.32)CFU/ml，内毒素数(0.39±0.35)EU/ml，化学消毒菌落为(42.67±39.04)CFU/ml，内毒素数为(0.42±0.38)EU/ml，热消毒和化学消毒效果无显著性差别，1次/d 热消毒菌落(38.27±37.11)为CFU/ml，内毒素数为(0.42±0.38)EU/ml，1次/3d热消毒菌落为(39.11±34.18)为CFU/ml，内毒素数为(0.39±0.35)EU/ml，1次/w 热消毒菌落为(42.08±39.87)CFU/ml，内毒素数为(0.42±0.41)EU/ml，经t捈煅椋3种频率下的热消毒效果无显著性差别。 结论 对透析供水系统采用热消毒并间断使用甲醛进行化学消毒是有效的，并且简便易行。

【Abstract】 Objective To investigate the effect of different kind of disinfections for dialysis water supplying system. Methods We tested and compared the amount of bacteria and endotoxin in water by using the chemical (formaldehyde) disinfection, and heat sterilization with the heat frequencies of once every day, every 3 days and every week.  Results The amount of bacteria and endotoxin were 38.90±36.32 CFU/ml and 0.42±0.38 EU/ml, respectively, in water with heat sterilization, and were 42.67±39.04 CFU/ml and 0.42±0.38 EU/ml, respectively, in water with chemical disinfection, without statistical differences in amount of bacteria and endotoxin between the two methods. The amount of bacteria and endotoxin were 38.27±37.11 CFU/ml and 0.42±0.38 EU/ml, respectively, in water with heat sterilization once a day, 39.11±34.18 CFU/ml and 0.39±0.35 EU/ml, respectively, in water with heat sterilization once every 3 days, and 42.08±39.87 CFU/ml and 0.42±0.41 EU/ml, respectively, once every week, without statistical differences in amount of bacteria and endotoxin among the three methods. Conclusion It is effective and simple for dialysis water supply system to use heat sterilization combined with intermittent formaldehyde chemical disinfection.