【摘要】 目的 研究收入和受教育水平对腹膜透析患者心理状态的影响。方法 在中国不同城市的5 家腹透中心进行横断面调查，入选2011 年4 月1 日至2011 年8 月31 日稳定在透3个月以上的共858名腹膜透析患者，记录患者的基本信息、透析充分性、生化评估、焦虑自评量表及抑郁自评量表评估结果，根据患者的人年平均收入和受教育水平分组，分析收入水平和受教育水平对患者焦虑抑郁状态的影响。结果 焦虑和抑郁的患病率分别为15.4%和58.3%；经年龄、性别、体重指数、透析龄、血红蛋白、血白蛋白、超敏C反应蛋白、透析Kt/V、残肾Kt/V校正后，受教育水平是抑郁的显著预测因子，与小学及以下学历患者相比，高中以上学历患者的抑郁风险将增加127.8%，而收入水平与焦虑抑郁状态无显著相关性。结论 受教育水平是腹膜透析患者抑郁的独立危险因素。

Objective To explore the impact of income and education levels on psychological status in patients on peritoneal dialysis (PD). Methods A total of 858 PD patients from 5 centers, treated for more than 3 months between April 1, 2011 and August 31, 2011, and with stable disease condition were enrolled in this study. General information, biochemical parameters, Self-rating Depression Scale (SDS), and Self-rating Anxiety Scale (SAS) were collected from the patients. The impact of income and education levels on prevalence of anxiety and depression were analyzed by binary logistic regression. Results The prevalence of anxiety and depression was 15.4% and 58.3%, respectively. Higher educational level was a significant predictor for depression in PD patients (β=1.259, P=0.019). Compared to the patients with elementary school education or lower, the risk of depression increased by 127.8% in patients with high school education or higher after adjustment for age, gender, body mass index, serum albumin, high- sensitive C reactive protein, dialysis age and renal urea clearance (β=2.278, P=0.012). However, there was no significant correlation between income level and prevalence of anxiety and depression (β=1.079, P=0.545). Conclusion Higher education level was an independent risk factor for depression in PD patients.