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临床研究

维持性血液透析患者甲状旁腺超声筛查的临床意义

  • 刘凤菊 勇强 程虹 卞维静
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  • 首都医科大学附属北京安贞医院1 超声诊断科 2 肾内科

收稿日期: 2013-11-04

  修回日期: 2013-09-11

  网络出版日期: 2014-03-12

The clinical significance of parathyroid ultrasound screening in hemodialysis patients

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Received date: 2013-11-04

  Revised date: 2013-09-11

  Online published: 2014-03-12

摘要

目的 探讨维持性血液透析(maintenance hemodialysis,MHD)患者实施甲状旁腺(parathyroid,PT)超声检查的临床意义;方法 收集MHD治疗1年以上患者的一般资料和相关实验室检查,根据全段甲状旁腺激素(intact parathyroid hormone,iPTH)水平分为A组(≥600pg/ml)和B组(<600pg/ml)实施PT超声检查。结果 有73例患者入选,其中A组55例,B组18例。A组PT超声检出率90.9%(50/55),B组PT超声检出率33.3%(6/18),差异有统计学意义(P<0.001);A、B两组间PT总体积存在显著性差异(t=4.171, P=0.021),单因素分析显示,iPTH水平与PT体积呈正相关(γ=0.543,P=0.039)。结论 iPHT水平高于600pg/ml的MHD患者,高度提示存在PT增生的可能。

本文引用格式

刘凤菊 勇强 程虹 卞维静 . 维持性血液透析患者甲状旁腺超声筛查的临床意义[J]. 中国血液净化, 2014 , 13(03) : 143 -145 . DOI: 10.3969/j.issn.1671-4091.2014.03.005

Abstract

Objective To investigate maintenance hemodialysis (MHD)for patients with parathyroid (PT) ultrasound clinical significance; Methods Collection MHD patients over one year of therapy and general information related laboratory examination, according to iPTH levels divided into group A (≥ 600pg/ml) and group B (<600pg/ml) implementation PT ultrasound. Results 73 patients were enrolled, including 55 cases of group A, B group 18 cases. Ultrasound PT detection rate: A group of 90.9% (50/55), B group of 33.3% (6/18), there was a significant difference between the two groups (P <0.001), PT total volume of significant differences also exit(t=4.171, P=0.021). Univariate analysis showed that iPTH levels were positively correlated with PT volume (γ = 0.543, P = 0.039). Conclusion iPHT levels above 600pg/ml of MHD patients is highly suggestive of the possible presence of PT hyperplasia.
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