目的调查了解廊坊市农村成年人群慢性肾脏病(chronic kidney disease,CKD)患病率并分析可能的危险因素。方法采用多阶段整群随机抽样法对廊坊市农村地区18 岁以上常住居民(居住时间＞6 个月)进行CKD 患病率、危险因素调查。分为CKD 组和对照组，选择性别、年龄、文化程度、高血压、糖尿病、血脂、血尿酸、肥胖等影响CKD 发生的相关因素进行比较分析，然后进行非条件多因素logistic回归分析。结果18062 人完成调查，CKD 患病率为10.75%；CKD 组(n=1942)与对照组(n=16120)比较，性别(χ2=87.927，P＜0.001)、年龄(t=11.855,P＜0.001)、收缩压(t=8.636，P＜0.001)、舒张压(t=4.812，P=0.028)、血尿酸(t=2.272，P=0.026)、空腹血糖(t=20.055，P=0.000)、三酰甘油(t=5.685，P=0.021)有显著差异；logistic 回归分析显示年龄(OR 1.440,95% CI 1.732～2.194)、高血压(OR 3.734,95% CI 2.764～6.423)和糖尿病(OR 4.560,95% CI 2.650～5.850)是CKD 患者发病的独立危险因素。结论廊坊市农村成年人群中CKD 具有较高的患病率，患者年龄、高血压、糖尿病病史和CKD 发病率密切相关，在农村地区开展CKD 的早期防治迫在眉睫。

Objective To investigate the prevalence of chronic kidney disease (CKD) in adults from rural area of Langfang and its related risk factors. Methods A random sample of adults older than 18 years and resident in the rural area of Langfang for more than 6 months was selected by multi- stage cluster sampling method. Clinical data including sex, age, educational level, hypertension, diabetes, blood lipids, uric acid and obesity were compared to assess the risk factors relating to CKD. The positive factors were then analyzed by logistic regression method. Results A total of 18,062 subjects were enrolled in this study, and the prevalence
of CKD was 10.75%. Analysis of the factors relating to CKD showed that female (P=0.000), age (P=0.000), hypertension (P=0.000), diabetes (P=0.000), blood lipids (P=0.021), uric acid (P=0.026) were the influencing factors. Multivariate logistic regression analyses showed that age (OR=1.440, 95% CI 1.732～2.194), hypertension (OR=3.734, 95%CI 2.764～6.423) and diabetes (OR=4.560, 95%CI 2.650～5.850) were the independent influencing factors for CKD patients. Conclusion The prevalence of CKD in adults from rural area of Langfang is higher. Female, hypertension, and diabetes are closely related to the prevalence of CKD. Early preventive measures should be emphasized to improve prognosis of the patients.