目的随访终末期肾脏病(end stage renal disease,ESRD)透析依赖患者冠状动脉旁路移植术(coronary artery bypass grafting,CABG)围术期和近中期生存率,并分析相关影响因素。方法回顾性分析26 例透析依赖的ESRD 患者行CABG 围术期和1、3、5 年的生存率。生存率使用Kaplan-Meier生存曲线表示,生存率影响因素使用Log Rank(Mantel-Cox)分析。结果围术期死亡3 例,死亡率11.5%。出院患者23 例,随访时间(2.9±2.4)年。1 年生存率90.0%,3 年生存率没有该时间点的用2 年近似76.9%,5 年生存率54.7%。高血压是影响术后生存率的风险因素(Log Rank χ2=5.870,P=0.015)。结论ESRD 患者行CABG 围术期死亡率高,术后近中期生存率不太满意,高血压是影响患者术后生存的危险因素。
Objective To follow up the peri-operative, short-term and medium-term outcomes after coronary artery bypass grafting (CABG) and to analyze the relevant influencing factors in patients with dialysisdependent end-stage renal disease (ESRD). Methods The survival rate during perioperative period and after CABG surgery for 1, 3 and 5 years in 26 dialysis-dependent ESRD patients undergoing CABG were retrospectively analyzed. Kaplan-Meier survival curve was used to show survival rate, and Log-rank (Mantel-Cox) test was used for identifying relevant influencing factors. Results Three patients died during perioperative period
(mortality 11.5%), and 23 patients discharged from the hospital successfully. The average follow-up time is 2.9±2.4 years. The survival rate is 90% in one year, 76.9% in 2 years after surgery (there is no survival rate in three years after surgery, approximate 2-year survival rate is then used), and 54.7% in 5 years after surgery. Log-rank(Mantel-Cox) test shows that hypertension is the only risk factor for postoperative survival rate (χ2=5.870, P=0.015). Conclusions Perioperative mortality after CABG in dialysis-dependent ESRD patients undergoing CABG is high, and the short and medium term survival rates (1 year, 2 years, 3 years after surgery) are not satisfactory. Hypertension is the only risk factor influencing postoperative survival rate.