多发性骨髓瘤肾病的血液净化治疗进展

熊瑞芳,封素娟,李寒,王世相

doi:10.3969/j.issn.1671-4091.2016.12.011

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中国血液净化 >

2016 , Vol. 15 >Issue 12: 694 - 696

DOI: https://doi.org/10.3969/j.issn.1671-4091.2016.12.011

综述

多发性骨髓瘤肾病的血液净化治疗进展

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1. 首都医科大学附属北京朝阳医院血液净化科

收稿日期: 2016-06-17

修回日期: 2016-07-25

网络出版日期: 2016-12-05

基金资助

国家自然科学基金(81200543)；北京市自然科学基金(7142057)；北京市卫生系统高层次卫生技术人才培养资助项目(2013-3-016)；北京市卫生系统高层次卫生技术人才培养项目(2013-3-016)；北京市医院管理局临床医学发展专项经费资助(ZYLX201408)；中国博士后科学基金资助项目(2015M581131)

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Recent advances in blood purification for the treatment of multiple myeloma nephropathy

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Received date: 2016-06-17

Revised date: 2016-07-25

Online published: 2016-12-05

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摘要

多发性骨髓瘤是血液系统的一种恶性肿瘤，常并发急性肾损伤。血液净化治疗能有效清除体内游离轻链促进患者肾功能恢复，改善预后。本文就多发性骨髓瘤肾病的血液净化治疗现状予以综述。

关键词： 多发性骨髓瘤肾病; 急性肾损伤; 血液净化

本文引用格式

熊瑞芳,封素娟,李寒,王世相 . 多发性骨髓瘤肾病的血液净化治疗进展[J]. 中国血液净化, 2016 , 15(12) : 694 -696 . DOI: 10.3969/j.issn.1671-4091.2016.12.011

Abstract

Multiple myeloma (MM) is a hematological malignancy. The acute kidney injury associated with MM is a cast nephropathy due to the increase of free monoclonal light chains (FLC) in plasma. Early and effective reduction of FLC by hemopurification can promote the recovery from kidney injury and improve the outcome in most patients. Here we review the current situation of hemopurification for MM nephropathy, in order to find an effective hemopurification therapy for acute kidney injury in MM.

Key words： Multiple myeloma nephropathy; Acute kidney injury; Blood purification

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