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专题与讲座

红细胞生成素低反应的原因及对策

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  • 1. 上海交通大学附属第六人民医院肾内科

收稿日期: 2017-01-04

  修回日期: 2017-06-22

  网络出版日期: 2017-08-12

基金资助

国家自然基金面上项目(81270824,81670657)、“十二五”国家科技支撑计划(2013BAI02B04)

Causes and management of low responses to erythropoietin

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Received date: 2017-01-04

  Revised date: 2017-06-22

  Online published: 2017-08-12

摘要

红细胞生成素(erythropoietin,EPO)临床是应用于慢性肾脏病患者贫血治疗,一部分患者因铁缺乏、炎症、氧化应激等因素出现红细胞生成素低反应的现象,影响红细胞生成素治疗效果,充分透析、补充营养、使用长效红细胞生成素等对策可改善红细胞生成素低反应。

本文引用格式

桂定坤,汪年松 . 红细胞生成素低反应的原因及对策[J]. 中国血液净化, 2017 , 16(08) : 509 -511 . DOI: 10.3969/j.issn.1671-4091.2017.08.002

Abstract

Erythropoietin (EPO) is used in clinical treatment of anemia in chronic kidney disease patients. Hyporesponsiveness of EPO occurs in some patients due to iron deficiency, inflammation, oxidative stress, etc. Adequate dialysis, improvement of nutritional status, and the use of long-acting EPO may have effect on the EPO hyporesponsiveness.
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