目的探讨血液透析用水处理系统反渗透膜的污染与清洗方法。方法根据血液透析用水处理系统的运行原理及反渗透膜污染物的性质，结合陕西省中医医院血液透析室反渗透膜清洗的实战经验，提出了血液透析用水处理系统反渗透膜的清洗方法。结果采用先碱洗(0.1%的氢氧化钠溶液)后酸洗(2%的柠檬酸溶液)，借助于水处理系统的消毒程序来完成反渗透膜清洗过程的方法，能够达到良好的清洗效果，恢复反渗透系统的性能。结论该方法可为广大血液透析行业反渗透膜的清洗提供参考和借鉴。

Objective To develop the detection of fouling and the methods of cleaning for reverse osmosis membrane in hemodialysis water treatment system. Methods According to the working principal of hemodialysis water treatment system, the nature of the pollutants on reverse osmosis membrane, and our working
experience of cleaning reverse osmosis membrane, we have developed cleaning methods for reverse osmosis membrane in hemodialysis water treatment system. Results We first washed the reverse osmosis membrane with 0.1% sodium hydroxide solution followed by 2% citric acid solution, and then sterilized the system by using the sterilization procedure settled in the water treatment system. This cleaning procedure worked well and restored the performance of reverse osmosis system. Conclusions This method provides a reference for the cleaning of reverse osmosis membrane for hemodialysis providers.