【摘要】骨病变是慢性肾脏病-矿物质和骨异常（CKD-MBD）的重要组成部分之一。对骨病变的及时诊断和评估，有助于合理防治。本文对于CKD-MBD 骨病变的骨转换标志物，不同骨病变（尤其是囊性纤维性骨炎、无动力骨病和骨质疏松等）的特点进行讨论，同时对于其诊治进展进行综述。

【Abstract】Bone disease was one of the main components of the chronic kidney disease-mineral and bone disorder (CKD-MBD). Early diagnosis and evaluation could be helpful for the prevention and treatment of bone disease. The markers of bone turnover in CKD-MBD, several types of bone diseases (especially osteitis fibrosa cystica, adynamic bone disease, osteoporosis, etc.) would be discussed, and the progresses of the diagnosis and treatment of bone diseases were reviewed in this article.