【摘要】目的了解女性维持性血液透析患者的整体疲乏状况，为改善女性维持性血液透析患者的疲乏状况提供理论依据。方法采用方便抽样，选取90 例来四川大学华西医院进行维持性血液透析的女性患者进行调查，通过患者一般资料问卷以及Piper 疲乏修订量表了解女性维持性血液透析患者的疲乏现状，采用多元逐步回归分析探讨其影响因素。结果本中心女性维持性血液透析患者疲乏得分为(5.080±1.782)分，处于中度疲乏。患者年龄(P=0.005)、月经情况(P=0.009)、并发症情况(P＜0.001)均是其影响因素，差异具有统计学意义。结论透析治疗中，医护人员应认识到女性维持性血液透析患者疲乏的症状及其影响因素，并针对不同情况展开干预措施，以改善患者的疲乏，同时提高生存质量。

【Abstract】Objective To understand the fatigue status in female maintenance hemodialysis (MHD) patients and to explore its influencing factors in order to provide the theoretical basis for the improvement of fatigue status in these patients. Methods A total of 90 female MHD patients in our hospital were recruited by convenient sampling method and were investigated by using the self-designed general information questionnaire and the revised Piper fatigue scale to understand the fatigue status in these patients. Multiple stepwise regression analysis was conducted to analyze its influencing factors. Results The fatigue score was (5.080± 1.782) points in the female MHD patients in this center. The influencing factors included patients' age (P= 0.005), menstrual condition (P=0.009) and complications (P＜0.001). Conclusion Doctors and nurses should recognize the fatigue symptoms and its influencing factors during dialysis for female MHD patients, and carry out intervention measures according to different situations so as to improve their fatigue status and the quality of life.