【摘要】认知障碍是慢性肾脏病的并发症之一，其发病受多种因素影响，继发性甲状旁腺功能亢进是重要影响因素之一，我们将从甲状旁腺激素(parathyroid hormone，PTH)、钙离子及维生素D 浓度3 个方面阐述其与认知障碍的关系及相关机制。

【Abstract】Cognitive impairment is one of the complications in chronic kidney disease patients. Many factors affect the cognitive impairment. The secondary hyperparathyroidism is one of the important influence factors for cognitive impairment. Here we discuss the mechanism of cognitive impairment from the viewpoints of abnormal levels of PTH, calcium ion and vitamin D in secondary hyperparathyroidism patients.