【摘要】目的探讨维持性血液透析患者疾病不确定感的现状及其与抑郁、希望的关系。方法采用一般资料调查表、疾病不确定感量表、抑郁自评量表、Herth 希望量表，对符合纳入标准的180 例维持性血液透析患者进行问卷调查。结果患者疾病不确定感总分为(74.23±7.64)分，抑郁总分为(53.04±9.59)分，希望总分为(32.33±3.05)分。疾病不确定感总分与抑郁总分呈正相关(r=0.429，P＜0.001)，与希望总分呈负相关(r=-0.348，P＜0.001)。多元线性回归分析显示，患者抑郁水平对疾病不确定感有正向预测作用(β=0.170，P＜0.001)，希望水平对疾病不确定感有负向预测作用(β=-0.398，P＜0.001)。结论维持性血液透析患者疾病不确定感处于较高水平，且与患者的抑郁、希望水平相关。
【Abstract】Objective To investigate the status of uncertainty in illness with maintenance hemodialysis (MHD) and its relationship with depression and hope. Methods Self-made questionnaire, Chinese version of Mishel disease uncertainty scale, depression self-rating scale, and Herth hope scale were used to investigate 180 MHD patients who met the inclusion criteria. Results The average total scores were 74.23±7.64 for Chinese version of Mishel disease uncertainty scale, 53.04±9.59 for depression self-rating scale, and 32.33±3.05 for Herth hope scale. The total score of uncertainty in illness was positively correlated with the total score of depression (r=0.429, P<0.001), and was negatively correlated with the total score of hope (r=-0.348, P<0.001). Multiple linear regression analysis showed that the level of depression could positively predict the level of uncertainty in illness (β=0.170, P<0.001), and the level of hope could negatively predict the level of uncertainty in illness (β=-0.398, P<0.001). Conclusions MHD patients had a higher level of uncertainty in illness, which was related to the levels of depression and hope.
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