【摘要】目的探讨维持性血液透析患者(maintenance hemodialysis,MHD)左心室舒张功能不全(left ventricular diastolic dysfunction, LVDD)的危险因素。方法根据超声指标将92 例患者分为LVDD 组及左心室舒张功能正常组，比较2 组之间人口学特征、临床及生化指标和水负荷状态，通过多因素Logistic 回归分析MHD 患者发生LVDD 的危险因素。结果23 例(25.00%)患者有LVDD。多因素Logistic
回归分析发现水负荷(OR=1.824,95% CI:1.124～2.960，P=0.015)是MHD 患者发生LVDD 的独立危险因素。结论MHD 患者伴容量超负荷是发生LVDD 的高危人群。
【Abstract】Objective To investigate the risk factors for left ventricular diastolic dysfunction (LVDD) in maintenance hemodialysis (MHD) patients. Method According to the diastolic function index, the 92 MHD patients were divided into two groups: LVDD group and normal left ventricular diastolic function group. Demographic characteristics, laboratory and body composition indexes were compared between the two groups. Logistic regression was used to analyze the risk factors for LVDD in MHD patients. Result In this cohort, 23(25.00%) patients had LVVD. Logistic analysis showed that overhydration (OR=1.824, 95% CI:1.124～2.960，P=0.015) was the independent risk factor for LVDD. Conclusion Patients with higher level of overhydration
were independently associated with an increased risk of LVDD.
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