【摘要】维生素D 结合蛋白(vitamin D binding protein，DBP)主要由肝脏合成，广泛分布于全身多个组织器官。近年来的研究发现，DBP 除了在血循环中结合、溶解和转运维生素D 及其代谢产物之外，还具有独立于维生素D 转运之外的免疫调节功能，与炎症和肿瘤的发生发展存在一定的关系。因此，本文综述了维生素D结合蛋白近期的研究进展，为今后相关领域的研究提供参考。

【Abstract】Vitamin D binding protein (DBP) is synthesized in liver and distributed in tissues and organs throughout the body. In recent years, it has been reported that DBP not only binds, dissolves and transports vitamin D and its metabolites in circulation, but also has immune regulation function independent of vitamin D transport, which is related to the transformation and development of inflammation and tumor. Therefore, we summarized the recent progresses in DBP research, in order to provide reference for further study in this field.