【摘要】慢性肾脏病(chronic renal disease，CKD)和心力衰竭(heart failure，HF)的患者都在增加，以致心肾共病面临着更高的再住院率、致残率和死亡率。目前很多针对HF 的临床试验皆排除终末期肾病(end-stage renal disease，ESRD)患者。极少部分研究涉及ESRD 患者，本文重点阐述在HF 治疗的相关研究中，有关ESRD患者的研究结果以及应用于临床的可行性。

【Abstract】The number of patients with chronic renal disease (CKD) and heart failure (HF) is increasing, leading to higher rates of hospitalization, disability and mortality in these patients. Most clinical trials for HF excluded the patients with end-stage renal disease (ESRD). Few HF studies involved patients with ESRD. This review focuses on the study results relating to the treatment of HF and the feasibility of clinical application in ESRD patients.