目的 探讨长江中下游地区梅雨季时潮湿环境下血液净化室发生丝状真菌污染的原因及处置对策。 方法 分析苏州大学附属儿童医院血液净化室2021年6月在每月常规微生物的培养时发现细菌菌落并有丝状真菌，期间血液净化治疗患儿有无感染情况及对策。 结果 血液净化室每月常规微生物培养监测，于2021年6月在水处理间透析用水(起始端)检测到细菌菌落76cfu/ml，其中有丝状真菌；透析1号机透析液细菌菌落6cfu/ml，其中有丝状真菌；透析2号机透析液细菌菌落4cfu/ml， 其中有丝状真菌。血液净化室立即启动应急预案，优先安置患儿，评估感染指针，分析丝状真菌污染原因，制定梅雨季血液净化室内相关消毒流程。 结论 通过在梅雨季增加针对透析室和水处理间物体表面、地面、环境及各类出风口的消毒频次，严格把控消毒质量，可明显抑制真菌的生长繁殖。
During the hot-humid climate in rainy season in the middle and lower regions of Yangtze river, filamentous fungi are easy to grow. The children with severe disease or immunocompromised status treated with blood purification are at high risk of getting nosocomial infection. In June 2021, the Blood Purification Room of Children's Hospital of Soochow University conducted the supervision of monthly microbial culture, and found that filamentous fungi were positive in several dialysis water samples and dialysis solutions, including microbial colony 76 cfu/ml in the initial terminal of the dialysis water from the water treatment room, microbial colony 6 cfu/ml in the dialysis solution from the No.1 dialysis machine, and microbial colony 4 cfu/ml in the dialysis solution from the No.2 dialysis machine. We immediately started an emergency plan, adjusted the dialysis regimen, monitored the inflammation markers and fungal infection indicators, analyzed the causes of filamentous fungi pollution, and revised the disinfection process in the blood purification room during rainy season. The fungal contamination can be effectively eliminated by strictly controlling the disinfection quality, and increasing the disinfection frequency for surfaces, ground, environment, air outlets in the dialysis room and water treatment room.
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