《脓毒症相关急性肾损伤(sepsis-associated acute kidney injury，SA-AKI)：第28届急性疾病质量倡议工作组(Acute Disease Quality Initiative workgroup，ADQI)的共识报告》(以下简称共识)于2023年2月发布，该共识涵盖了临床定义和流行病学、病理生理学、液体管理策略的影响、生物标志物在风险分层和诊断治疗指导中的作用、体外血液净化及创新疗法和儿童患者的SA-AKI等6部分内容，共计34条共识。该共识为全球第一个关于SA-AKI的ADQI专家共识，为SA-AKI的诊疗提供了较准确的方向和框架。本文对该共识前5部分关于成人SA-AKI的要点予以解读，同时结合四川大学华西医院在SA-AKI血液净化方面的应用经验进行分享，为医务工作者对SA-AKI的诊疗实践提供参考与借鉴。

《Sepsis-associated acute kidney injury(SA-AKI):28th Acute Disease Quality Initiative workgroup: The ADQI Consensus Report》(hereinafter referred to as Consensus) was published in February 2023. The consensus covers six parts of clinical definition and epidemiology, pathophysiology, the impact of fluid management strategies, the role of biomarkers in risk stratification and diagnostic treatment guidance, extracorporeal blood purification and innovative therapies, and SA-AKI in pediatric patients, totaling 34 articles of consensus. This consensus is the first global ADQI expert consensus on SA-AKI,and provides a more accurate direction and framework for the diagnosis and treatment of SA-AKI. This article interprets the main points of adults in the first 5 parts of the consensus, and shares the application experience of West China Hospital of Sichuan University in SA-AKI blood purification, which can provide reference for medical workers in the diagnosis and treatment of SA-AKI.