慢性肾脏病(chronic kidney disease，CKD)是一种全球性的健康问题，其发病机制错综复杂，持续的低度炎症状态是其本质特征。近年来，全身免疫炎症指数(systemic immune inflammation index，SII)作为评估炎症状态的新工具能更好的反映患者全身炎症水平，受到了广泛关注，它的计算公式为血小板计数×中性粒细胞计数/淋巴细胞计数，因为容易获取、价格低廉、易于计算等优势，成为一个“热点问题”被广泛应用于临床。本文旨在综述SII在CKD患者中的研究进展，探讨其与CKD发生、发展的关系，以及该指数在疾病监测和预后评估中的应用价值，以期为后续相关研究提供有价值的参考。

Chronic kidney disease (CKD) is a global health problem with a complex pathogenesis characterized by a persistent low-grade inflammatory state. In recent years, the systemic immune inflammatory index (SII) has received widespread attention as a new tool for assessing the inflammatory state. SII can better reflect the systemic inflammation level of the patient, and has been widely used in clinical practice because of its advantages of easy access, low price, and ease of calculation. The purpose of this article is to review the research progresses in SII in CKD patients, to explore the relationship between SII and occurrence and development of CKD, to assess the value of SII in disease monitoring and prognostic assessment, and to provide the useful references for subsequent studies.