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综述

相位角在慢性肾脏病合并肌少症患者中的研究进展

  • 陈燕芬 ,
  • 王景福
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  • 024206 承德,1承德医学院附属医院肾内科

收稿日期: 2024-06-17

  修回日期: 2024-11-26

  网络出版日期: 2025-03-12

基金资助

2023年度河北省医学科学研究课题计划(20231382)

Research progress in the changes of phase angle in chronic kidney disease patients with sarcopenia

  • CHEN Yan-Fen ,
  • WANG Jing-Fu
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  • Department of Nephrology, The Affiliated Hospital of Chengde Medical College, Chengde 024206, China

Received date: 2024-06-17

  Revised date: 2024-11-26

  Online published: 2025-03-12

摘要

生物电阻抗分析(bioelectrical impedance analysis,BIA)是一种简单的、快速的、无创的评估身体成分的方法,相位角(phase angle,PA)作为BIA衍生物,可用于肌肉质量和肌肉强度测量,在肌少症的诊断和预测中存在价值。肌少症与慢性肾脏病(chronic kidney disease,CKD)患者的不良健康结局有关。有研究表明PA可能是评估CKD患者肌肉健康状况的主要标志。本文就PA在CKD合并肌少症患者中的研究进展进行综述,以期在CKD患者筛查、评估、监测肌少症提供依据。

本文引用格式

陈燕芬 , 王景福 . 相位角在慢性肾脏病合并肌少症患者中的研究进展[J]. 中国血液净化, 2025 , 24(03) : 231 -234 . DOI: 10.3969/j.issn.1671-4091.2025.03.013

Abstract

Bioelectrical impedance analysis (BIA) is a simple, rapid, and noninvasive method for assessing body composition. Phase angle (PA) that derives from BIA can be used for the measurement of muscle mass and strength and thus for the diagnosis and prediction of sarcopenia. Sarcopenia is associated with poor health outcomes in chronic kidney disease (CKD) patients.  Studies have suggested that PA may be an important marker for assessing muscle health status in CKD patients. In this article, we present a review about recent progress in the changes of PA in CKD patients with sarcopenia, with the aim of providing a basis for screening, evaluating, and monitoring sarcopenia in CKD patients.

参考文献

[1]WILSON S, MONE P, JANKAUSKAS S S, et al.Chronic kidney disease: Definition,updated epidemiology,staging,and mechanisms of increased cardiovascular risk[JOL][J].The Journal of Clinical Hypertension, 2021, 23(4):831-834 [2]朱思懿, 洪航, 边学燕, 等.慢性肾脏病流行病学研究进展[J].预防医学, 2023, 35(9):770-773 [3]SABATINO A, CUPPARI L, STENVINKEL P, et al.Sarcopenia in chronic kidney disease: what have we learned so far?[JOL][J].Journal of Nephrology, 2021, 34(4):1347-1372 [4]CRUZ-JENTOFT A J, BAEYENS J P, BAUER J M, et al.Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People[JOL][J].Age and Ageing, 2010, 39(4):412-423 [5]SANTANA N de M, PINHO C P S, DA SILVA C P, et al.Phase Angle as a Sarcopenia Marker in Hospitalized Elderly Patients[JOL][J].Nutrition in Clinical Practice: Official Publication of the American Society for Parenteral and Enteral Nutrition, 2018, 33(2):232-237 [6]DOS REIS A S, SANTOS H O, LIMIRIO L S, et al.Phase Angle Is Associated With Handgrip Strength but Not With Sarcopenia in Kidney Transplantation Patients[JOL][J].Journal of Renal Nutrition: The Official Journal of the Council on Renal Nutrition of the National Kidney Foundation, 2019, 29(3):196-204 [7]UEMURA K, YAMADA M, OKAMOTO H.Association of bioimpedance phase angle and prospective falls in older adults[JOL][J].Geriatrics & Gerontology International, 2019, 19(6):503-507 [8]KILIC M K, KIZILARSLANOGLU M C, ARIK G, et al.Association of Bioelectrical Impedance Analysis-Derived Phase Angle and Sarcopenia in Older Adults[JOL][J].Nutrition in Clinical Practice: Official Publication of the American Society for Parenteral and Enteral Nutrition, 2017, 32(1):103-109 [9]毛雅, 姚颖.生物电阻抗分析的临床应用[J].华中科技大学学报医学版, 2022, 51(5):706-711 [10]CANCELLO R, BRUNANI A, BRENNA E, et al.Phase angle (PhA) in overweight and obesity: evidence of applicability from diagnosis to weight changes in obesity treatment[JOL][J].Reviews in Endocrine & Metabolic Disorders, 2023, 24(3):451-464 [11]YAMADA Y, YOSHIDA T, MURAKAMI H, et al.Phase angle obtained via bioelectrical impedance analysis and objectively measured physical activity or exercise habits[JOL][J].Scientific Reports, 2022, 12(1):17274-- [12]BALLARIN G, VALERIO G, ALICANTE P, et al.Bioelectrical Impedance Analysis (BIA)- Derived Phase Angle in Children and Adolescents: A Systematic Review[JOL][J].Journal of Pediatric Gastroenterology and Nutrition, 2022, 75(2):120-130 [13]DI VINCENZO O, MARRA M, DI GREGORIO A, et al.Bioelectrical impedance analysis (BIA) -derived phase angle in sarcopenia: A systematic review[JOL][J].Clinical Nutrition (Edinburgh, Scotland), 2021, 40(5):3052-3061 [14]DA SILVA1 B R, ORSSO1 C E, GONZALEZ2 M C, et al.Phase angle and cellular health: inflammation and oxidative damage[JOL][J].Reviews in Endocrine & Metabolic Disorders, 2023, 24(3):543-562 [15]刘宝, 刘光凤, 宫继斌, 等.相位角在危重症患者中的应用[J].中国中西医结合急救杂志, 2023, 30(4):503-506 [16]CHATZIPETROU V, BéGIN M J, HARS M, et al.Sarcopenia in Chronic Kidney Disease: A Scoping Review of Prevalence,Risk Factors,Association with Outcomes,and Treatment[JOL][J].Calcified Tissue International, 2022, 110(1):1-31 [17]李宇玫, 王来亮, 罗群.慢性肾脏病肌少症发病机制研究进展[J].中华老年医学杂志, 2018, 37(5):594-597 [18]DUARTE M P, ALMEIDA L S, NERI S G R, et al.Prevalence of sarcopenia in patients with chronic kidney disease: a global systematic review and meta-analysis[JOL][J].Journal of Cachexia, Sarcopenia and Muscle, 2024, 15(2):501-512 [19]MOON S J, KIM T H, YOON S Y, et al.Relationship between Stage of Chronic Kidney Disease and Sarcopenia in Korean Aged 40 Years and Older Using the Korea National Health and Nutrition Examination Surveys (KNHANES IV-2,3,and V-1,2),2008-2011[JOL][J].PloS One, 2015, 10(6):e0130740-- [20]WILKINSON T J, MIKSZA J, YATES T, et al.Association of sarcopenia with mortality and end-stage renal disease in those with chronic kidney disease: a UK Biobank study[JOL][J].Journal of Cachexia, Sarcopenia and Muscle, 2021, 12(3):586-598 [21]CHEN X, CAO M, LIU M, et al.Association between sarcopenia and cognitive impairment in the older people: a meta-analysis[JOL][J].European Geriatric Medicine, 2022, 13(4):771-787 [22]WOO J.Nutritional interventions in sarcopenia: where do we stand?[JOL][J].Current Opinion in Clinical Nutrition and Metabolic Care, 2018, 21(1):19-23 [23]刘建强, 彭晖.慢性肾脏病合并肌少症的研究进展[J].中华肾脏病杂志, 2023, 39(6):479-484 [24]聂磊, 钟爱民.慢性肾脏病合并肌少症[J].实用临床医学, 2023, 24(4):113-117 [25]CRUZ-JENTOFT A J, BAHAT G, BAUER J, et al.Sarcopenia: revised European consensus on definition and diagnosis[JOL][J].Age and Ageing, 2019, 48(1):16-31 [26]CHEN L K, WOO J, ASSANTACHAI P, et al.Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment[JOL][J].Journal of the American Medical Directors Association, 2020, 21(3):300-307 [27]AKAMATSU Y, KUSAKABE T, ARAI H, et al.Phase angle from bioelectrical impedance analysis is a useful indicator of muscle quality[JOL][J].Journal of Cachexia, Sarcopenia and Muscle, 2022, 13(1):180-189 [28]乔威佳.相位角与老年肌少症的相关性分析[D].南昌大学医学部, 2023. [29]姚克青, 丛明华, 王甦, 等.探讨晚期肿瘤患者“相位角”与肌肉减少症发生率的相关性[C]//中国营养学会, 亚太临床营养学会, 江苏省科学技术协会, 中国疾病预防控制中心营养与健康所, 农业农村部食物与营养发展研究所.营养研究与临床实践——第十四届全国营养科学大会暨第十一届亚太临床营养大会、第二届全球华人营养科学家大会论文摘要汇编.北京市朝阳区桓兴肿瘤医院; 医学科学院肿瘤医院; , 2019:2.DOI:10.26914/c.cnkihy.2019.010386. [30]张文博, 程梅, 李淑凤, 等.相位角在肌少症患者中的应用研究[J].中国骨质疏松杂志, 2023, 29(6):922-925 [31]SHIN J, HWANG J H, HAN M, et al.Phase angle as a marker for muscle health and quality of life in patients with chronic kidney disease[JOL][J].Clinical Nutrition (Edinburgh, Scotland), 2022, 41(8):1651-1659 [32]VAISHYA R, MISRA A, VAISH A, et al.Hand grip strength as a proposed new vital sign of health: a narrative review of evidences[JOL][J].Journal of Health, Population, and Nutrition, 2024, 43(1):7-- [33]BEBERASHVILI I, AZAR A, SINUANI I, et al.Bioimpedance phase angle predicts muscle function,quality of life and clinical outcome in maintenance hemodialysis patients[JOL][J].European Journal of Clinical Nutrition, 2014, 68(6):683-689 [34]WARD L C, BRANTLOV S.Bioimpedance basics and phase angle fundamentals[JOL][J].Reviews in Endocrine & Metabolic Disorders, 2023, 24(3):381-391 [35]LUKASKI H C, KYLE U G, KONDRUP J.Assessment of adult malnutrition and prognosis with bioelectrical impedance analysis: phase angle and impedance ratio[JOL][J].Current Opinion in Clinical Nutrition and Metabolic Care, 2017, 20(5):330-339 [36]GIGLIO J, KAMIMURA M A, LAMARCA F, et al.Association of Sarcopenia With Nutritional Parameters,Quality of Life,Hospitalization,and Mortality Rates of Elderly Patients on Hemodialysis[JOL][J].Journal of Renal Nutrition: The Official Journal of the Council on Renal Nutrition of the National Kidney Foundation, 2018, 28(3):197-207 [37]SUN D S, LEE H, YIM H W, et al.The impact of sarcopenia on health-related quality of life in elderly people: Korean National Health and Nutrition Examination Survey[JOL][J].The Korean Journal of Internal Medicine, 2019, 34(4):877-884 [38]SHIN J, HWANG J H, HAN M, et al.Phase angle as a marker for muscle health and quality of life in patients with chronic kidney disease[JOL][J].Clinical Nutrition (Edinburgh, Scotland), 2022, 41(8):1651-1659 [39]RIBEIRO H S, NERI S G R, OLIVEIRA J S, et al.Association between sarcopenia and clinical outcomes in chronic kidney disease patients: A systematic review and meta-analysis[JOL][J].Clinical Nutrition (Edinburgh, Scotland), 2022, 41(5):1131-1140 [40]BORRELLI S, PROVENZANO M, GAGLIARDI I, et al.Sodium Intake and Chronic Kidney Disease[JOL][J].International Journal of Molecular Sciences, 2020, 21(13):4744-- [41]BELLIDO D, GARCíA-GARCíA C, TALLURI A, et al.Future lines of research on phase angle: Strengths and limitations[JOL][J].Reviews in Endocrine & Metabolic Disorders, 2023, 24(3):563-583
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