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Chinese Journal of Blood Purification >

2010 , Vol. 9 >Issue 12: 662 - 664

DOI: https://doi.org/10.3969/j.issn.1671-4091.2010.11.00

临床研究

Clinical observation of nutrition status in patients using high flux membrane for hemodialysis

  • XU Feng-bo ,
  • LIU Hui-lan ,
  • ZUO Li ,
  • WU Hua ,
  • LI Ji-jun ,
  • CAI Li ,
  • TANG Tian-qing ,
  • YIN Pei ,
  • CHENG Xu-yang ,
  • BAO Yun-fei
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  • 1Department of Nephrology, Beijing Fuxing Hospital, Capital University of Medical Science, Beijing 100038, China; 2Department of Nephrology, Peking University Institute of Nephrology, Peking University First Hospital, Beijing 100034, China; 3Department of Nephrology, Beijing Hospital, Beijing 100730, China; 4Department of Nephrology, First Hospital Affiliated to the PLA General Hospital, Beijing 100037, China

Received date: 2010-07-15

  Revised date: 1900-01-01

  Online published: 2010-12-12

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Abstract

Objective This prospective and self-controlled study was designed to evaluate whether change from low-flux hemodialysis to high-flux hemodialysis could improve patients’ nutrition status. Methods We recruited 136 patients on maintenance low-flux hemodialysis. We then changed the low-flux dialyzer to high-flux F60 or FX60 dialyzer for hemodialysis without changing any other dialysis prescriptions. Plasma albumin, appetite score and subjective global assessment (SGA) were assessed before the change and after the change for 6 months. Results Plasma albumin remained unchanged in all patients after the change. In patients whose albumin increased lower than 25 percentile, plasma albumin was 36.4±3.1g/L, and 39.9±3.9g/L (P<0.001) before the change and after the change for 3 and 6 months, respectively. Appetite score increased (P=0.0049) after the change for 6 months. SAG score also increased (P<0.05) after the change for 3 and 6 months. Conclusions The results show that the shift from low-flux to high-flux hemodialysis improves the nutrition status in maintenance hemodialysis patients.

Key words： Low flux hemodialysis; Nutrition status

Cite this article

XU Feng-bo , LIU Hui-lan , ZUO Li , WU Hua , LI Ji-jun , CAI Li , TANG Tian-qing , YIN Pei , CHENG Xu-yang , BAO Yun-fei . Clinical observation of nutrition status in patients using high flux membrane for hemodialysis[J]. Chinese Journal of Blood Purification, 2010 , 9(12) : 662 -664 . DOI: 10.3969/j.issn.1671-4091.2010.11.00

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