【Abstract】 Objective To investigate the sleep quality in patients on maintenance hemodialysis of long session hemodialysis. Methods sleep quality was evaluated using the Athens Insomnia Scale (AIS), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS). Forty patients on maintenance hemodialysis were equally divided into two groups according to their scores of sleep quality: hemodialysis (HD) group, and long session hemodialysis (LSHD) group. In HD group, hemodialysis was performed 4h a session and three times a week. In LSHD group, hemodialysis was delivered 8h a session and three times a week. The test lasted for 6 months. Results Kt/V was significant higher in LSHD group than in HD group (P＜0.05). Significant differences in PSQI, ESS scores were found between the two groups.  Conclusion Sleep disorder is very common in hemodialysis patients. Increase of hemodialysis dose can improve sleep quality.