Research progress in the relationship between uremic toxins and sarcopenia in chronic kidney disease&nbsp;patients

FANG Lv- gui, XUAN Ming- yang, DU Ya- ting, RAO Xiang- rong

doi:10.3969/j.issn.1671-4091.2022.07.013

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Chinese Journal of Blood Purification >

2022 , Vol. 21 >Issue 07: 521 - 524

DOI: https://doi.org/10.3969/j.issn.1671-4091.2022.07.013

Research progress in the relationship between uremic toxins and sarcopenia in chronic kidney disease patients

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Department of Nephrology, South District of Guang-An-Men Hospital, China Academy of Chinese Medical Sciences, Beijing 102600, China; Graduate School of Beijing University of Chinese Medicine, Beijing 100029, China; Graduate School of
China Academy of Chinese Medical Sciences, Beijing 100700, China; Department of Nephrology, Guang-AnMen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China

Received date: 2021-12-23

Revised date: 2022-03-29

Online published: 2022-07-12

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Abstract

Sarcopenia in chronic kidney disease patients is caused by many factors, of which one is the
uremic toxins, which distinguishes CKD sarcopenia from other sarcopenias. We have reviewed and analyzed
the literature about the effect of uremic toxins on sarcopenia in order to comprehend the pathogenesis of sarcopenia and to find out the references for the treatment strategies of sarcopenia in CKD patients. Here we summarized the recent progresses in the relationship between uremic toxins and CKD sarcopenia, in an attempt to
explore a meaningful research subject and a novel strategy for the treatment of CKD sarcopenia by removal of
uremic toxins.

Key words： Uremic toxin; Sarcopenia; Review

Cite this article

FANG Lv- gui, XUAN Ming- yang, DU Ya- ting, RAO Xiang- rong . Research progress in the relationship between uremic toxins and sarcopenia in chronic kidney disease patients[J]. Chinese Journal of Blood Purification, 2022 , 21(07) : 521 -524 . DOI: 10.3969/j.issn.1671-4091.2022.07.013

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