Peritoneal dialysis related infection is one of the main complications in peritoneal dialysis, and Staphylococcus aureus (s. aureus) is one of the common pathogens. Nasal carrying s. aureus plays an important role in its endogenous infection. This paper investigates the relationship between nasal carrying s. aureus and the occurrence of peritonitis, and analyzes the effect of eliminating nasal carrying s. aureus on the prevention of peritoneal dialysis related infection.