Objective This study intended to conduct a cross-sectional survey of anemia and iron status distribution characteristics and drug use in regional maintenance hemodialysis patients to clarify the relationship between relevant indicators and provide data support for the development of optimal anemia management strategies. Methods Twelve blood purification centers in three provinces including Jiangsu Province, Anhui Province and Jiangxi Province were selected. Maintenance hemodialysis patients from September 2021 to December 2021 were included. General demographic data and laboratory parameters before dialysis were collected. Relevant analysis methods were used to describe hemoglobin (Hb) reaching standards, anemia and iron status distribution characteristics of multicenter maintenance hemodialysis patients, and to explore the related factors affecting the control rate of Hb. Results A total of 1814 patients who met the criteria were included in this study, including 1116 males and 698 females, with a mean age of 58.0±14.0 years. The overall control rate of Hb was 48.5%, and the Hb distribution and control rate were significantly different among the sub-centers (P < 0.001). The vast majority of patients had serum ferritin (SF) < 200 μg/L and 2% had SF more than 1000 μg/L. Transferrin Saturation (TSAT) ranged from 20-49% in 64.8% of patients. For every 1% change in TSAT, the OR of Hb reaching target was 1.029 (P=0.023, 95% CI=1.004-1.055). Conclusion The overall control rate of Hb of sample units was not satisfactory, most patients had moderate or slight iron reserve, and very few patients had iron overload. There were significant differences in Hb and iron status distribution characteristics among sub-centers. TSAT was an independent protective factor for good control rate of Hb.
XING Jie
,
WANG Gui-Hua
,
ZHANG Liu-Ping
,
XIE Qing-Lei
,
LU Wen
,
CHEN Feng-Ling
,
FANG Ya-Xiang
,
HE Wei-Ming
,
DING Hong
,
WANG De-Guang
,
PAN You-Wen
,
JIN Wei-Min
,
LI Yu-Dan
,
LIU Jian-Jing
,
WEI Shan-Zhai
,
FANG Li-Ming
,
CHEN Xiao-Lan
,
ZHANG Xiao-Liang
. Regional multicenter investigation of anemia and iron status in maintenance hemodialysis patients[J]. Chinese Journal of Blood Purification, 2023
, 22(1)
: 1
-6
.
DOI: 10.3969/j.issn.1671-4091.2023.01.001
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