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The pathogenesis and treatment of sarcopenia in end-stage renal disease patients on maintenance dialysis

  • WAN Li ,
  • WANG Mei
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  • 1Blood Purification Center, Department of Nephrology, Peking University International Hospital, Beijing 102206, China; 2Department of Nephrology, Peking University People’s Hospital, Beijing 100044, China

Received date: 2022-09-29

  Revised date: 2022-11-16

  Online published: 2023-02-12

Abstract

Sarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle mass, strength and function. End-stage renal disease (ESRD) patients are at a higher risk of accelerated muscle wasting due to the renal diseases itself, various complications, dialysis treatment and reduced activity from dialysis treatment. The incidence of sarcopenia is higher in dialysis patients and the mortality will be increased in dialysis patients with sarcopenia, highlighting the great importance of early prevention, detection and treatment of muscle wasting. In this article, we summarize the pathogenesis, diagnosis and treatment of sarcopenia in ESRD patients on maintenance dialysis.

Cite this article

WAN Li , WANG Mei . The pathogenesis and treatment of sarcopenia in end-stage renal disease patients on maintenance dialysis[J]. Chinese Journal of Blood Purification, 2023 , 22(02) : 128 -132 . DOI: 10.3969/j.issn.1671-4091.2023.02.011

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