Renal transplantation is the best renal replacement therapy for uremic patients. A successful kidney transplantation often relies on blood purification, and different blood purification methods also affect the prognosis of kidney transplant patients. Therefore, it is particularly important to explore the impact of various blood purification techniques in the perioperative period of kidney transplantation. This article reviews the research progresses of various blood purification methods in the perioperative period of kidney transplantation.