Encapsulation Peritoneal Sclerosis (EPS) is a rare and serious complication in long-term peritoneal dialysis patients, with poor prognosis and high mortality rate. EPS is a chronic and insidious disease that often difficult to identify in its early stages. It is characterized by progressive and extensive fibrotic thickening of the peritoneum, peritoneal sclerosis，which causes progressive obstruction and encapsulation of the bowel. Till now, the pathogenesis of EPS remains uncertain. Early detection and timely intervention can effectively prevent the progression of EPS, and multidisciplinary combination treatment is needed. However, EPS has not been widely recognized in China, especially for doctors in primary hospitals, which can easily lead to missed diagnosis or misdiagnosis. In order to guide physician to comprehensively understand the pathogenesis, clinical characteristics, and prevention and treatment strategies of EPS in peritoneal dialysis (PD) patients, identify EPS risk factors, diagnose and treat EPS early so as to delay its progression, the Blood Purification Center Branch of Chinese Hospital Association organized experts in the field of peritoneal dialysis in China to develop this expert consensus.