Objective The aim of this study was to investigate the burden of cardiovascular disease (CVD) in hemodialysis (HD) patients in China, so as to provide evidences for conducting a multicenter study on CVD in the future. Methods The HD Working Group of the HD Branch of the Chinese Hospital Association developed a questionnaire, and pushed the questionnaire through Questionnaire Star to the medical staff of HD centers in China from 2024.1.11-2024.1.18 to investigate the prevalence of CVDs and the screening status. Results A total of 186 valid questionnaires were collected, covering 19 provinces, 4 autonomous regions and 4 municipalities. Coronary artery disease and vascular calcification were the most common types of CVD in HD patients, with the proportion of prevalence exceeding 40% in 55.9% and 62.4% of HD centers, respectively; followed by ischemic stroke, with relatively low proportions of atrial fibrillation and cerebral hemorrhage. In 68.6% of HD centers, the annual mortality rate of patients was less than 10%. In terms of CVD screening, 58.6% of HD centers performed echocardiography for patients once a year, but only 25 (13.4%) arranged for lateral abdominal plain films for patients once a year, and only 15 (8.1%) HD centers performed pulse wave velocity for patients once a year. What’s more, 39.8% of HD centers considered patient compliance to be poor, and 83.3% of medical staff were willing to participate in studies related to the burden of CVD in HD patients. Conclusion The proportion of HD patients with CVD is high in China, especially coronary artery disease and vascular calcification, but numerous HD centers failed to conduct regular CVD screening, and patient compliance was poor. CVD screening and management should be strengthened in the future to reduce the burden of CVD disease in HD patients.
WANG Yan
,
ZHAO Xin-Ju
,
WEI Tao
. Research on the burden of cardiovascular disease in hemodialysis patients in China[J]. Chinese Journal of Blood Purification, 2024
, 23(10)
: 736
-740
.
DOI: 10.3969/j.issn.1671-4091.2024.10.002
[1]Thurlow JS, Joshi M, Yan G, et al.Global Epidemiology of End-Stage Kidney Disease and Disparities in Kidney Replacement Therapy[J].Am J Nephrol, 2021, 52(2):98-107
[2]梁耀先, 赵新菊, 韦洮.中国血液透析行业发展调研报告[J].中国血液净化, 2024, 23(5):321-329
[3]Robinson BM, Akizawa T, Jager KJ, Kerr PG, Saran R, Pisoni RL.Factors affecting outcomes in patients reaching end-stage kidney disease worldwide: differences in access to renal replacement therapy, modality use, and haemodialysis practices[J].Lancet, 2016, 388(10041):294-306
[4]Naylor KL, Kim SJ, McArthur E, Garg AX, McCallum MK, Knoll GA.Mortality in Incident Maintenance Dialysis Patients Versus Incident Solid Organ Cancer Patients: A Population-Based Cohort[J].Am J Kidney Dis , 2019, 73(6):765-776
[5]赵新菊, 甘良英, 牛庆雨, 陈育青, 侯凡凡, 倪兆慧, 陈晓农, 梁馨玲, 左力.中国血液透析患者死亡原因及特点分析-DOPPS研究的启示[J].中国血液净化, 2022, 21(2):89-93
[6]Roberts MA, Polkinghorne KR, McDonald SP, Ierino FL.Secular trends in cardiovascular mortality rates of patients receiving dialysis compared with the general population[J].Am J Kidney Dis , 2011, 58(1):64-72
[7]Jankowski J, Floege J, Fliser D, Bohm M, Marx N.Cardiovascular Disease in Chronic Kidney Disease: Pathophysiological Insights and Therapeutic Options[J].Circulation, 2021, 143(11):1157-1172
[8]Webster AC, Nagler EV, Morton RL, Masson P.Chronic Kidney Disease[J]. Lancet, 2017, 389(10075):1238-1252
[9]Matsushita K, Ballew SH, Wang AY, Kalyesubula R, Schaeffner E, Agarwal R.Epidemiology and risk of cardiovascular disease in populations with chronic kidney disease[J].Nat Rev Nephrol, 2022, 18(11):696-707
[10]Cannata-Andia JB, Martin-Carro B, Martin-Virgala J, et al.Chronic Kidney Disease-Mineral and Bone Disorders: Pathogenesis and Management[J].Calcif Tissue Int, 2021, 108(4):410-422
[11]Kidney Disease: Improving Global Outcomes CKDMBDUWG.KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD)[J]. Kidney Int Suppl (2011), 2017, 7(1):1-59
[12]国家肾脏疾病临床医学研究中心.中国慢性肾脏病矿物质和骨异常诊治指南概要[J].肾脏病与透析肾移植杂志, 2019, 28(1):52-57
[13]Townsend RR.Arterial Stiffness in CKD: A Review[J].Am J Kidney Dis, 2019, 73(2):240-247
[14]Zhang H, Li G, Yu X, et al.Progression of Vascular Calcification and Clinical Outcomes in Patients Receiving Maintenance Dialysis[J].JAMA Netw Open, 2023, 6(5):e2310909-
[15]曹明聪, 马晓迎, 贾汝福, 王亚飞, 潘可丽, 胡静.基于医护协作的药品信息化管理对门诊血液透析患者透析用药依从性及生化指标的影响[J].中国血液净化, 2024, 23(1):71-74
