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Refractory peritoneal dialysis-related peritonitis caused by Berneroxus infection: report of a case and review of the literature

  • FU Bi-Ling ,
  • SUI Xiao-Lu ,
  • HOU Jie ,
  • LIU Yu-Hong ,
  • CHEN Ji-Hong
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  • Department of Nephrology, The Second Affiliated Hospital of Shenzhen University, Shenzhen 518035, China;  2Department of Nephrology, Baoan District People's Hospital, Shenzhen 518101, China

Received date: 2024-10-08

  Revised date: 2025-04-15

  Online published: 2025-07-12

Abstract

Objective  To explore the diagnosis and treatment of a rare Benacovirus infection in a patient with peritoneal dialysis-associated peritonitis.  Methods  A case of refractory peritoneal dialysis-related peritonitis caused by Benacovirus infection was retrospectively analyzed, and the related literature was reviewed.  Results  The pathogen of Benacovirus was identified by high-throughput sequencing of MetaCAP microbial nucleic acids from patient's peritoneal drainage fluid. Continuous peritoneal lavage and drainage using double-lumen tubes combined with oral administration of doxycycline gradually clarified the peritoneal drainage fluid and reduced white blood cell counts in the fluid. Follow-up for 2 months after removal of the drainage tube showed no recurrence.  Conclusion  When conventional methods fail to detect the pathogen, MetaCAP sequencing can be helpful to provide etiological evidence and treatment strategy for the peritoneal dialysis-associated peritonitis. Coxiella burnetii is a rare pathogen causing peritoneal dialysis-associated peritonitis, requiring prompt recognition and appropriate treatment.

Cite this article

FU Bi-Ling , SUI Xiao-Lu , HOU Jie , LIU Yu-Hong , CHEN Ji-Hong . Refractory peritoneal dialysis-related peritonitis caused by Berneroxus infection: report of a case and review of the literature[J]. Chinese Journal of Blood Purification, 2025 , 24(07) : 614 -616 . DOI: 10.3969/j.issn.1671-4091.2025.07.015

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